Preprints
Noback M, Zhang G, White N, Barrow JC, Carr GV. Post-weaning social isolation increases ΔFosB/FosB protein expression in the prefrontal cortex and hippocampus in mice. bioRχiv. Link
2020
Byers S, Buchler IP, DePasquale M, Rowley HL, Kulkarni RS, Pinder L, Kolobova A, Li C, Au V, Akuma D, Zhang G, Wei H, Cheetham SC, Barrow JC, Carr GV. Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility. Accepted in Psychopharmacology 2020. Link
DeBrosse A, Wheeler AM, Barrow JC, Carr GV. Inhibition of Catechol-O-methyltransferase Does Not Alter Effort-Related Choice Behavior in a Fixed Ratio/Concurrent Chow Task in Male Mice. Front. Behav. Neurosci. 2020; 14:73. Link
2019
Ernst G, Akuma D, Au V, Buchler IP, Byers S, Carr GV, Defays S, de Leon P, Demaude T, DePasquale M, Durieu V, Huang Y, Jigorel E, Kimos M, Kolobova A, Montel F, Moureau F, Poslusney M, Swinnen D, Vandergeten M-C, Van houtvin N, Wei H, White N, Wood M, Barrow JC. Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol-O-Methyltransferase. ACS Med. Chem. Lett. 2019; 10(11): 1573-1578. Link
Zhang G, Buchler IP, DePasquale M, Wormald M, Liao G, Wei H, Barrow JC, Carr GV. Development of a PC12 Cell Based Assay for Screening Catechol-O-methyltransferase Inhibitors. ACS Chemical Neurosci. 2019; 10(10):4221-4226. Link
Lohoff FW, Carr GV, Brookshire B, Ferraro TN, Lucki I. Deletion of the vesicular monoamine transporter 1 (vmat1/slc18a1) gene affects dopamine signaling. Brain Res. 2019; 1712: 151-157. Link
2018
Buchler I, Akuma D, Au V, Carr G, de Leon P, DePasquale M, Ernst G, Huang Y, Kimos M, Kolobova A, Poslusney M, Wei H, Swinnen D, Montel F, Moureau F, Jigorel E, Schulze MED, Wood M, Barrow JC. Optimization of 8-Hydroxquinolines as Inhibitors of Catechol-O-Methyltransferase. J Med Chem. 2018; 61(21): 9647-9665. Link
2017
Carr GV, Maltese F, Sibley DR, Weinberger DR, Papaleo F. The Dopamine D5 Receptor is Involved in Working Memory. Front Pharmacol. 2017: 8:666. Link
2016
Carr GV, Chen J, Yang F, Ren M, Yuan P, Tian Q, Bebensee A, Zhang GY, Du J, Glineburg P, Xun R, Akhile O, Akuma D, Pickel J, Barrow JC, Papaleo F, Weinberger DR. KCNH2-3.1 expression impairs cognition and alters neuronal function in a model of molecular pathology associated with schizophrenia. Mol Psychiatry. 2016; 21(11): 1517-1526. Link
Detrait ER, Carr GV, Weinberger DR, Lamberty Y. Brain catechol-O-methyltransferase (COMT) inhibition by tolcapone counteracts recognition memory deficits in normal and chronic phencyclidine-treated rats and in COMT-Val transgenic mice. Behav Pharmacol. 2016; 27(5): 415-421. Link
Papaleo F, Yang F, Paterson C, Palumbo S, Carr GV, Wang Y, Floyd K, Huang W, Thomas CJ, Chen J, Weinberger DR, Law AJ. Behavioral, neurophysiological, and synaptic impairment in a transgenic neuregulin1 (NRG1-IV) murine schizophrenia model. J Neurosci. 2016; 36(17):4859-4875. Link
2013
Carr GV, Jenkins KA, Weinberger DR, Papaleo F. Loss of dysbindin-1 in mice impairs reward-based operant learning by increasing impulsive and compulsive behavior. Behav Brain Res. 2013;241:173-184. Link
2011
Carr GV, Schechter LE, Lucki I. Antidepressant and anxiolytic effects of selective 5-HT6 receptor agonists in rats. Psychopharmacology. 2011; 213(2-3):499-507. Link
Carr GV, Lucki I. The role of serotonin subtypes in treating depression: a review of animal studies. Psychopharmacology. 2011;213(2-3):265-287. Link
2010
Tahsili-Fahadan P, Carr GV, Harris GC, Aston-Jones G. Modafinil blocks reinstatement of extinguished opiate-seeking in rats: mediation by a glutamate mechanism. Neuropsychopharmacology. 2010; 35(11):2203-2210. Link
Carr GV, Lucki I. Comparison of the kappa-opioid receptor antagonist DIPPA in tests of anxiety-like behavior between Wistar Kyoto and Sprague Dawley rats. Psychopharmacology. 2010; 210(2):295-302. Link
Carr GV, Bangasser DA, Bethea T, Young M, Valentino RJ, Lucki I. Antidepressant-like effects of kappa-opioid receptor antagonists in Wistar Kyoto rats. Neuropsychopharmacology. 2010; 35(3):752-763. Link
2008
Howard O, Carr GV, Hill TE, Valentino RJ, Lucki I. Differential blockade of CRF-evoked behaviors by depletion of norepinephrine and serotonin in rats. Psychopharmacology. 2008; 199(4):569-582. Link
Carr GV, Mague SD. p38: the link between the kappa-opioid receptor and dysphoria. J Neurosci. 2008; 28(10):2299-3000. Link